News

Paper of the Month (Jan 2018)

13 Feb 2018

Hosseinzadeh P., Bhardwaj, G., Mulligan, V. K., Shortridge, M. D., Craven, T. W., et al. (2017) Comprehensive computational design of ordered peptide macrocycles. Science, 358 (6369): 1461-1466.

http://science.sciencemag.org/content/358/6369/1461

Paper of the Month (Dec 2017)

24 Jan 2018

Gerken P. A., Wolstenhulme J. R., Tumber A., Hatch S. B., Zhang Y. et al. (2017) Discovery of a Highly Selective Cell-Active Inhibitor of the Histone Lysine Demethylases KDM2/7. Angew. Chem. Int. Ed., 56: 15555-15559.

http://dx.doi.org/10.1002/anie.201706788

Paper of the Month (November 2017)

08 Dec 2017

Kategaya L., Di Lello P., Rougé L., Pastor R., Clark K.R., Drummond J., et al. (2017) USP7 small-molecule inhibitors interfere with ubiquitin binding. Nature, 550: 534.

https://www.nature.com/articles/nature24006

Paper of the Month (Oct 2017)

01 Nov 2017

Lasko L.M., Jakob C.G., Edalji R.P., Qiu W., Montgomery D., Digiammarino E.L., et al. (2017) Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours. Nature550(7674): 128-132. 

http://www.nature.com/nature/journal/v550/n7674/full/nature24028.html

Paper of the Month (Aug 2017)

02 Oct 2017

Jiang H., Deng R., Yang X.,  SHang J., Lu S., Zhao Y., Song K., Liu X., Zhang Q., Chen E., Wu G., Li J., Chen G., Yu J. & Zhang J. (2017) Peptidomimetic Inhibitors of APC-Asef interaction block colorectal cancer migration.  Nat. Chem. Biol. 13, 994-1001 

http://www.nature.com/nchembio/journal/v13/n9/full/nchembio.2442.html?foxtrotcallback=true