Paper of the Month (Jan 2018)

13 Feb 2018

Hosseinzadeh P., Bhardwaj, G., Mulligan, V. K., Shortridge, M. D., Craven, T. W., et al. (2017) Comprehensive computational design of ordered peptide macrocycles. Science, 358 (6369): 1461-1466.

Paper of the Month (Dec 2017)

24 Jan 2018

Gerken P. A., Wolstenhulme J. R., Tumber A., Hatch S. B., Zhang Y. et al. (2017) Discovery of a Highly Selective Cell-Active Inhibitor of the Histone Lysine Demethylases KDM2/7. Angew. Chem. Int. Ed., 56: 15555-15559.

Paper of the Month (November 2017)

08 Dec 2017

Kategaya L., Di Lello P., Rougé L., Pastor R., Clark K.R., Drummond J., et al. (2017) USP7 small-molecule inhibitors interfere with ubiquitin binding. Nature, 550: 534.

Paper of the Month (Oct 2017)

01 Nov 2017

Lasko L.M., Jakob C.G., Edalji R.P., Qiu W., Montgomery D., Digiammarino E.L., et al. (2017) Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours. Nature550(7674): 128-132.

Paper of the Month (Aug 2017)

02 Oct 2017

Jiang H., Deng R., Yang X.,  SHang J., Lu S., Zhao Y., Song K., Liu X., Zhang Q., Chen E., Wu G., Li J., Chen G., Yu J. & Zhang J. (2017) Peptidomimetic Inhibitors of APC-Asef interaction block colorectal cancer migration.  Nat. Chem. Biol. 13, 994-1001