Paper of the Month (Oct 2017)

01 Nov 2017

Lasko L.M., Jakob C.G., Edalji R.P., Qiu W., Montgomery D., Digiammarino E.L., et al. (2017) Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours. Nature550(7674): 128-132.

Paper of the Month (Aug 2017)

02 Oct 2017

Jiang H., Deng R., Yang X.,  SHang J., Lu S., Zhao Y., Song K., Liu X., Zhang Q., Chen E., Wu G., Li J., Chen G., Yu J. & Zhang J. (2017) Peptidomimetic Inhibitors of APC-Asef interaction block colorectal cancer migration.  Nat. Chem. Biol. 13, 994-1001

Paper of the Month (July 2017)

10 Jul 2017

Grison C.M., Burslem G.M., Miles J.A., Pilsl L.K.A., Yeo D.J., Imani Z., Warriner S.L., Webb M.E. & Wilson A.J. (2017) Double quick, double click reversible peptide “stapling”. Chem. Sci., 8(7): p. 5166-5171.!divAbstract


Paper of the Month (June 2017)

14 Jun 2017

 McCoull, W., Abrams, RD., Anderson, E., Blades, K., Barton, P. et al. (2017) Discovery of Pyrazolo[1,5-a]pyrimidine B-Cell Lymphoma 6 (BCL6) Binders and Optimization to High Affinity Macrocyclic Inhibitors. Journal of Medicinal Chemistry 60 (10), 4386-4402


Paper of the Month (May 2017)

07 Jun 2017

 Niu, X., Brahmbhatt, H., Mergenthaler, P., Zhang, Z., Sang, J., Daude, M., Ehlert, F. G. R., Diederich, W. E., Wong, E., Zhu, W., Pogmore, J., Nandy, J. P., Satyanarayana, M., Jimmidi, R. K., Arya, P., Leber, B., Lin, J., Culmsee, C., Yi, J. & Andrews, D. W. (2017) A Small-Molecule Inhibitor of Bax and Bak Oligomerization Prevents Genotoxic Cell Death and Promotes Neuroprotection. Cell Chemical Biology 24, 493-506.e495