News

Paper of the Month (March 2017)

10 Apr 2017

 

Kumar, S., Hamilton, A. D., (2017) Alpha-Helix Mimetics as Modulators of Alpha-Beta Self-Assembly, J. Am. Chem. Soc. (in press)

http://pubs.acs.org/doi/abs/10.1021/jacs.6b09734

Paper of the Month (February 2017)

13 Feb 2017

Paper of the month for February

Johannes, J. W., Bates, S., Beigie, C., Belmonte, M. A., Breen, J., et al. (2017) Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors. ACS Med. Chem. Lett. 8, 239-244.

http://dx.doi.org/10.1021/acsmedchemlett.6b00464

Paper of the Month (January 2017)

13 Feb 2017

Here is the belated paper of the month for January

Sarnowski, M. P., Kang, C. W., Elbatrawi, Y. M., Wojtas, L. & Del Valle, J. R. (2017) Peptide N-Amination Supports beta-Sheet Conformations. Angew. Chem. Int. Ed. 56, 2083-2086. 

http://dx.doi.org/10.1002/anie.201609395

Paper of the Month (December 2016)

11 Jan 2017

Happy New Year to all PPI-Net members, here is the belated December's paper of the month

Spencer-Smith et al. (2017). Inhibition of RAS function through targeting an allosteric regulatory site. Nature Chemical Biology 13, 62-68 .

http://dx.doi.org/10.1038/nchembio.2231

 

Paper of the Month (October 2016)

02 Nov 2016

October's paper of the month

Kotchy et al. (2016). The Mcl-1 inhibitor S63845 is tolerable and effective in diverse cancer models. Nature 538, 477-482.

doi:10.1038/nature19830