Paper of the Month (August 2016)
03 Oct 2016
Sorry belated paper of the month for August.
Sable, R., Durek, T., Taneja, V., Craik, D. J., Pallerla, S., Gauthier, T., and Jois, S. Constrained Cyclic Peptides as Immunomodulatory Inhibitors of the CD2:CD58 Protein–Protein Interaction,
ACS Chem. Biol. 2016, 11, 2366-2374
Transfer of Ownership
14 Jun 2016
Ownership of PPI-Net has been transferred to the EPSRC Programme Grant being led by Prof. Andy Wilson, University of Leeds.
As part of this transfer, the website will be updated in due course.
Free PPI-Net compound library
11 Sep 2014
PPI-Net is delighted to announce that a compound collection that was purchased using PPI-Net funds is now available for free of charge (except for postage) to all PPI-Net members. This PPI Net compound collection is a library of 1534 compounds that can be used for screening.
This is stored in Leeds and is intended to assist the community by making copies available free of charge as a starting point for screens and assays. GSK have also generously contributed £10,000 towards further expansion of the library.
PPI-Net members can request access to the request sytem in order to view the SD files and order compounds by emailing us.
3rd Young Researchers Symposium
11 Apr 2014
The PPI-Net Young Researchers Symposium has taken place on the 7th April 2014 at Imperial College London
Congratulations to the winners of the prizes that were presented by Professor Geoff Barton from the University of Dundee:
Diana Monteiro (University of Leeds) “Structural studies of pantothenase biosynthesis”
Colin Robinson (Institute of Cancer Research) for the poster entitled “Small Molecule Probes for Protein-Protein Interactions: Mimicking Beta-Sheet Motifs”
and Sozan Qarani (University of Nottingham) for the poster entitled “Investigating the role of the non-integrin laminin receptor in the pathogenesis of meningococcal meningitis”
Paper of the Month
10 Mar 2014
Srinivasan, P.; Yasgar, A.; Luci, D. K.; Beatty, W. L.; Hu, X.; Andersen, J.; Narum, D. L.; Moch, J. K.; Sun, H.; Haynes, J. D.; Maloney, D. J.; Jadhav, A.; Simeonov, A.; Miller, L. H. Nat Commun 2013, 4. Disrupting malaria parasite AMA1–RON2interaction with a small molecule prevents erythrocyte invasion.