Paper of the Month (December 2016)
11 Jan 2017
Happy New Year to all PPI-Net members, here is the belated December's paper of the month
Spencer-Smith et al. (2017). Inhibition of RAS function through targeting an allosteric regulatory site. Nature Chemical Biology 13, 62-68 .
Paper of the Month (October 2016)
02 Nov 2016
October's paper of the month
Kotchy et al. (2016). The Mcl-1 inhibitor S63845 is tolerable and effective in diverse cancer models. Nature 538, 477-482.
Paper of the Month (September 2016)
12 Oct 2016
September's paper of the month
Akcay, G., M. A. Belmonte, B. Aquila, C. Chuaqui, A. W. Hird, M. L. Lamb, P. B. Rawlins, N. Su, S. Tentarelli, N. P. Grimster and Q. Su (2016). "Inhibition of Mcl-1 through covalent modification of a noncatalytic lysine side chain." Nat Chem Biol advance online publication.
Paper of the Month (August 2016)
03 Oct 2016
Sorry belated paper of the month for August.
Sable, R., Durek, T., Taneja, V., Craik, D. J., Pallerla, S., Gauthier, T., and Jois, S. Constrained Cyclic Peptides as Immunomodulatory Inhibitors of the CD2:CD58 Protein–Protein Interaction,
ACS Chem. Biol. 2016, 11, 2366-2374
Transfer of Ownership
14 Jun 2016
Ownership of PPI-Net has been transferred to the EPSRC Programme Grant being led by Prof. Andy Wilson, University of Leeds.
As part of this transfer, the website will be updated in due course.