Amy Rees

Bellamy-Carter, J., Mohata, M., Falcicchio, M., Basran, J., Higuchi, Y., Doveston, R.G. & Leney, A.C. (2021) Discovering protein–protein interaction stabilisers by native mass spectrometry. Chem. Sci., doi:10.1039/D1SC01450A. http://dx.doi.org/10.1039/D1SC01450A

Wendt, M., Bellavita, R., Gerber, A., Efrém, N.-L., van Ramshorst, T., et al. (2021) Bicyclic β-Sheet Mimetics that Target the Transcriptional Coactivator β-Catenin and Inhibit Wnt Signaling. Angew. Chem. Int. Ed. 60, 25, 13937-13944. https://doi.org/10.1002/anie.202102082

Hong, S. H., Yoo, D.Y., Conway, L., Richards-Corke, K.C., Parker, C.G. and Arora, P.S. (2021) A Sos proteomimetic as a pan-Ras inhibitor. Proc. Natl. Acad. Sci. U. S. A. 118, e2101027118, doi:10.1073/pnas.2101027118.

Ekanayake, A. I., Sobze, L., Kelich, P., Youk, J. Bennett, N.J. et al. (2021) Genetically Encoded Fragment-Based Discovery from Phage-Displayed Macrocyclic Libraries with Genetically Encoded Unnatural Pharmacophores. J. Am. Chem. Soc. 143, 5497-5507, https://doi.org/10.1021/jacs.1c01186

Chang, D., Feng, S., Girik, V., Riezman, H. & Winssinger, N. (2021) Luciferase Controlled Protein Interactions J. Am. Chem. Soc. 143, 10, 3665–3670, https://doi.org/10.1021/jacs.0c11016

de Vries, R. M. J. M., Meijer, F. A., Doveston, R. G., Leijten-van de Gevel, I. A. & Brunsveld, L. (2021) Cooperativity between the orthosteric and allosteric ligand binding sites of RORγt Proc. Natl. Acad. Sci. U. S. A. 118, doi:10.1073/pnas.2021287118

Bartling, C. R. O., Jensen, T.M.T., Henry, S.M., Colliander, A.L., Sereikaite, V. et al. (2021) Targeting the APP-Mint2 Protein–Protein Interaction with a Peptide-Based Inhibitor Reduces Amyloid-β Formation. JACS. https://doi.org/10.1021/jacs.0c10696

Słabicki, M., Yoon, H., Koeppel, J., Nitsch, L., Roy Burman, S.S. et al. (2020) Small-molecule-induced polymerization triggers degradation of BCL6. Nature 588, 164–168 https://doi.org/10.1038/s41586-020-2925-1

Henley, M. J., Linhares, B.M., Morgan, B.S., Cierpicki, T., Fierke, C.A. & Mapp, A.K. (2020) Unexpected specificity within dynamic transcriptional protein–protein complexes. PNAS 117, 27346-27353, doi:10.1073/pnas.2013244117

Wolter, M., Valenti, D., Cossar, P.J., Levy, L.M., Hristeva, S., et al. (2020) Fragment‐Based Stabilizers of Protein-Protein Interactions through Imine‐Based Tethering. Angew. Chem. Int. Ed., doi:10.1002/anie.202008585